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INTRODUCTION TO GM

GMO Myths and Facts front page.jpg

SCIENCE SUPPORTS REGULATION OF GENE EDITING

Plant tissue cultures

GENE EDITING: UNEXPECTED OUTCOMES AND RISKS

Damaged DNA on fire

GENE EDITING MYTHS AND REALITY

A guide through the smokescreen

Gene Editing Myths and Reality

ON-TARGET EFFECTS OF GENE EDITING

Damaged DNA

New GMO wheat may "silence" vital human genes

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Published: 08 April 2013
Twitter

NOTE: The article below on the risks posed by CSIRO's new GM "gene-silencing" wheat dates from last year but is still highly topical thanks to the release of New Zealand scientist Prof Jack Heinemann and colleagues' release this year of a peer-reviewed paper on the inadequate risk assessment of 'gene-silencing' type GMOs:

Heinemann, J., et al. (2013). "A comparative evaluation of the regulation of GM crops or products containing dsRNA and suggested improvements to risk assessments." Environment International 55: 43–55. http://www.sciencedirect.com/science/article/pii/S0160412013000494

The original article features a video press conference in which Prof Heinemann and Dr Judy Carman clearly explain the risks that the wheat poses to humans:
http://www.digitaljournal.com/article/332822

There's no indication that CSIRO has even tested the wheat on animals.
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Scientists: New GMO wheat may "silence" vital human genes
By Elliott Freeman
Digital Journal, 9 October 2012
http://www.digitaljournal.com/article/332822

Australian scientists are expressing grave concerns over a new type of genetically engineered wheat that may cause major health problems for people that consume it.

University of Canterbury Professor Jack Heinemann announced the results of his genetic research into the wheat, a type developed by Australia's Commonwealth Scientific and Industrial Research Organisation (CSIRO), at a press conference last month.

"What we found is that the molecules created in this wheat, intended to silence wheat genes, can match human genes, and through ingestion, these molecules can enter human beings and potentially silence our genes," Heinemann stated. "The findings are absolutely assured. There is no doubt that these matches exist."
Flinders University Professor Judy Carman and Safe Food Foundation Director Scott Kinnear concurred with Heinemann's analysis.

"If this silences the same gene in us that it silences in the wheat -- well, children who are born with this enzyme not working tend to die by the age of about five," Carman said.

Digital Journal contacted Heniemann and Kinnear for more information on their research and future actions they may take regarding this issue.

"To date we have not heard from CSIRO, nor are we aware that CSIRO has released any safety studies into the GM wheat," Kinnear said in an email response. "We are in the final stages of drafting a formal letter to CSIRO which will be requesting further information and asking for them to undertake the studies that are recommended in our reports."

According to the researchers, extended testing should be performed before the wheat is put on store shelves. "We firmly believe that long term chronic toxicological feeding studies are required in addition to the detailed requests made by Heinemann for the DNA sequences used," Kinnear stated.

"The industry routinely does feeding studies anyway, so it should not be too much more difficult to do long term (lifetime) studies and include inhalation studies," Heinemann added. "These should be tuned to the way people would be exposed to the product."

The researchers also cautioned consumers against eating the wheat if it is approved prematurely. "I would advise citizens to request that these tests be done and the evidence meet with their standards of scientific rigour if in the end it is approved for use," said Heinemann.

If the concerns surrounding CSIRO's GM wheat are not resolved, the issue could end up in court, according to Kinnear: "If CSIRO was to consider moving towards human feeding trials without conducting these studies, we would be looking at what legal avenues are available to stop them."

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